Sam

Sam is a hunter as well as a Man of Letters, along with his older brother Dean. He is one of the main protagonists of Supernatural. Both Sam and Dean are related to the Winchester and Campbell families - a Letters family and a Hunting family respectively. The pair also share a bloodline withCain and Abel. Because of this, Sam was pre-destined to be the vessel of the fallen archangel Lucifer (whilst Dean was Michael's). Sam is friends with angel Castiel, prophet Kevin Tran, the demonMeg and former lover turned enemy of demon Ruby. He is also the reluctant ally of demon Crowley and for a time was forced to be an unknowing and unwilling vessel for the angel Gadreel (before expelling him).

After the demon Azazel killed their mother, both Sam and Dean were raised in the hunting life by their father John. Sam left the Hunting life to pursue a career in law, and most likely would have married his college sweetheart Jessica Moore. At the series' start, Sam was reluctant to start hunting again. When Jessica was killed, he was pushed back into the hunting life. However, he has been repeatedly known to try and back out of Hunting in the hope of finally having a normal life as he wanted.

Sam is very mentally strong, evidenced by his ability to overpower possession by Lucifer. It has been argued that he is the smarter of the Winchester brothers, although Sam himself would disagree.

Over time Sam has accepted the Hunting lifestyle and has repeatedly sacrificed himself for the greater good, highlighting his selfless nature.